- Duke as Casper
- Chloe as Amelia Harvey
- The Once-ler's Mom (from Dr. Seuss' The Lorax) as Amber Whitmire
- Max as Dr. James Harvey
- Mel as Vic DePhillippi
- Vector (from Despicable Me) as Dibs
- Dr. Nefario (from Despicable Me) as Stinkie
- Mr. O'Hare (from Dr. Seuss' The Lorax) as Fatso
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