• David (from All Dogs Go to Heaven 2) as Alex
  • Sean (from Journey 2: The Mysterious Island) as Tuck Simms
  • Hank (from Journey 2: The Mysterious Island) as Munch
  • Anne-Marie (from All Dogs Go to Heaven) as Emma
  • Snowball as Dr. Lawrence Masden
  • Silas Ramsbottom (from Despicable Me 2) as Calvin
  • Mr. O'Hare (from Dr. Seuss' The Lorax) as Mookie
  • Buddy as Pawn Shop Owner
  • E.B. (from HOP) as Joey
  • Chloe as Charlie
  • The Once-ler's Mom (from Dr. Seuss' The Lorax) as Dusty
  • Gidget as Tuck's Mom
  • Duke as Emma's Dad
  • Max as Blake
  • Max and Duke's Owner as Emma's Mom
  • Gru (from Despicable Me) as Security Guard

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