• Duke as Optimus Prime
  • Max as Bumblebee
  • Hank (from Journey 2: The Mysterious Island) as Autobot Drift
  • Mel as Lockdown
  • Dr. Nefario (from Despicable Me) as Cade Yeager
  • Grammy Norma (from Dr. Seuss' The Lorax) as Tessa Yeager
  • Snowball as Shane
  • Vector (from Despicable Me) as Harold Attinger
  • Gru (from Despicable Me) as Lucas
  • Max and Duke's Owner as Darcy

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