- Anthony "Hub" Hubbard as Ash Ketchum
- Major General William Devereaux as Pikachu
- CIA Officer Elise Kraft as Misty
- FBI Special Agent Frank Haddad as Brock
- Khalil Saleh as Gary Oak
- Samir Nazhde as Tracey
- Sheik Akhmed bin Talal as Harley
- FBI Agent Tina Osu as May
- FBI Agent Mike Johanssen as Buizel
- FBI Agent Danny Sussman as Beldum
- FBI Agent Floyd Rose as Magnemite
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