- Moe as Calvin
- Homer as Hobbes (Both have names starting with "H")
- Marge as Calvin's Mom
- Principal Skinner as Calvin's Dad
- Lisa as Susie
- Edna Krappenbel as Rosalyn
- Ms. Moran (from Arthur) as Calvin's Teacher
- Mr. Hanny (from Arthur) as Calvin's Principal
- Grandpa Abe as Calvin's Dummy
- and more
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