- Mr. Burns as Dick Dastardly
- Nelson as Muttley
- Dolph as Klunk
- Kearney as Zilly
- Sideshow Mel as Yankee Doodle Pigeon
- Jimbo as The Mad Scientist
- Lisa as Hilda
- Russ Cargill as The Sea Captain
- Apu Nahasapeemapetilon as Sam Swami
- Fat Tony as The General
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