Version 1

  • Principal Skinner as Garfield
  • Ned Flanders as Odie
  • Stan Marsh (from South Park) as Jon Arbuckle
  • Wendy Testaburger (from South Park) as Liz Arbuckle
  • Allison Taylor as Penelope
  • Homer as Orson
  • Milhouse as Booker
  • Martin as Sheldon
  • Moe as Roy
  • Barney as Wade
  • Bart as Bo
  • Marge as Lanolin
  • Lisa as Cloe
  • Maude Flanders as Mrs. Chicken
  • and more

Version 2

  • Homer as Garfield (both fat and lazy)
  • Santa's Little Helper as Odie
  • Ned Flanders as Jon Arbuckle
  • Maude Flanders as Liz Arbuckle
  • Marge as Arlene (cameo)
  • Bart as Nermal
  • Lisa as Penelope
  • Barney as Wade
  • Grandpa Abe as Sheldon
  • Maggie as Lanolin
  • Mr. Burns as The Weasel 
  • and others

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