The Spirit of Sakura and Ephraim is a fan-fiction TV Show created by Pikachufreak.
The show resolves on Sakura (from Trouble's Brewing and Espeon, Not Included) and Ephraim (from The Grass Route) the main characters. They were both a married couple. Their daughter is Mandy whose boyfriend is Billy (both from The Grim Adventures of Billy and Mandy) and their mothers are Edna Krabappel (from The Simpsons) and Andrea (from The Corsola Caper). The Series premiered on May 26, 1997 and is currently in its 18th Season.