- Michael "Mike" O'Halloran as Ash Ketchum
- Doug Roberts as Pikachu
- James "Jim" Duncan as Drew
- Susan Franklin as Misty
- Harlee Claiborne as Brock
- Patty Duncan Simmons as May
- Roger Simmons as Buizel
- Lisolette Mueller as Dawn
- Harry Jernigan as Professor Birch
- Mayor Robert "Bob" Ramsay as Mewtwo
- Kappy as Bulbasaur
- Scott as Max
- and more
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