The Big Bang Theory

The unseen character of Mrs. Wolowitz on The Big Bang Theory took a trip to Florida and passed away there in her sleep right after the actress who provided her voice, Carol Ann Susi, passed away from cancer complications. There are quite a few episodes dealing with the in-universe aftermath, including the characters holding a memorable toast for her and her son, Howard trying to get her ashes right after they were misplaced.

All-New Shining Time Station

When Barbara Hamilton passed away in 1996, Bobo Lewis passed away in 1998 and Ari Magder passed away in 2012, the characters of Ginny Johnson, Midge Smoot and Dan Jones have passed away in the sequel reboot.

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