Thomas, Percy, James, Donald, Douglas, James, Edward, Henry, Gordon, Bertie, Boco, Duck, Oliver, Twlight Sparkle, and their friends(along with Mac Foster, Bloo, Wilt, Eduardo, Coco, and Frankie Foster) have traveled to London, England and met Pongo, Perdita, and their 15 puppies. They soonlearned that the puppies were stolen by Jasper and Horace. They have been hired by the most outrageous Disney villain of all, Cruella De Vil, whom Diesel, Arry, Bert, Terrence, and Duchess, work for. Can Thomas, Twlight Sparkle, Percy, Toby, Gwen Stacy, Edward, Duck, Donald, Douglas, Oliver Bash, Dash, Ferdinand, Luke, Mac Foster, Bloo, Wilt, Eduardo, Coco, Frankie Foster, Helen Parr, Bob Parr, Manny and Ellie help Pongo and Perdita get Gordon, Henry, James, Boco, Bertie, Applejack, Pinkie Pie, Shining Armor,Fluttershy, Rainbow Dash, Violet Parr, Dash Parr, and Rarity and the puppies back to London before the villains do any harm on them? You be the judge.
Like in Pooh's Adventures of 101 Dalmatians, Simba, Timon and Pumbaa's Adventures of 101 Dalmatians, and Yogi Bear's Adventures of 101 Dalmatians, Gordon, Henry, James, Peter Parker, Dash Parr, Violet Parr, Rainbow Dash, Pinkie Pie will be kidnapped with Pongo and Perdita's fifteen puppes.
Devious Diesel, Iron Arry, Iron Bert, Gordon, Boco, Henry, James, Bertie the Bus, Terrence, Duchess, Manny, Ellie, The Incredibles (Helen Parr, Bob Parr, Dash Parr, and Violet Parr), Peter Paker, and Gwen Stacy, guest star in the film.
This film marks the first debut of Frankie Foster, Mac Foster, Bloo, Coco, Wilt and Eduardo from Foster's Home for Imaginary Friends.This is a NTSC film, but unlike LionKingRulezAgain1's Simba, Timon and Pumbaa's Adventures of 101 Dalmatians, and DisneyDaniel93's Pooh's Adventures of 101 Dalmatians and TheCityMaker's Yogi Bear's Adventures of 101 Dalmatians this will use the Platinum Edition version of 101 Dalmatians (As both have used the original version).