• Noah as Osmosis Jones
  • Owen as Drix
  • Alejandro as Thrax
  • Emma as Leah Estrogen
  • Dave as Mayor Phlemming
  • Tyler as Tom Colonic
  • Don as The Police Chief
  • Trent as Frank Detorre
  • Carrie as Shane Detorre
  • Gwen as Mrs.Boyd
  • Cody as Bob

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