- Tugg Speedman as Arthur
- Kirk Lazarus as Brain
- Jeff Potnoy as Binky
- Alpa Chino as Buster
- Kevin Sandusky as David
- Sergeant John "Four Leaf" Tayback as Mr. Ratburn
- Damien Cockburn as Alberto Molina
- Cody Wunderwood as Ed Crosswire
- Rob Slolom as George
- Tran as Rattles
- Les Grossman as Dr. Frederick Fugue
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