- Emily, Mavis, Molly, Marion, Lady or Rosie (Thomas the Tank Engine & Friends)
- Lillie Lightship or Sally Seaplane (TUGS)
- Sunshine (Salty's Lighthouse)
- Emily (Theodore Tugboat)
- Zephie (Chuggington)
- Princess Peach (Super Mario Bros.)
- Penelope Pitstop (Wacky Races/The Perils of Penelope Pitstop)
- Amy Rose (Sonic the Hedgehog)
- Babs Bunny (Tiny Toon Adventures)
- Abby (Cubix: Robots For Everyone)
- Sally or Cindy Lou-Who (Dr. Seuss)
- Sarah Hall-Small (The Wubbulous World Dr. Seuss)
- Namine, Kairi, Aqua, or Xion (Kingdom Hearts)
- Marge Simpson (The Simpsons)
- Lois Griffin (Family Guy)
- Wendy Testaburger (South Park)
- Isabella Garcia Shapiro (Phineas and Ferb)
- Yo (Fanboy and Chum Chum)
- Numbuh 362 (Codename: Kids Next Door)
- Tessie Bear (Noddy's Toyland Adventures)
- Princess Sherry (Rocket Knight Adventures)
- Helga (Hey Arnold)
- Blossom or Bubbles (Powerpuff Girls)
- Jeanette (Alvin and the Chipmunks)
- Jen Scotts (Power Rangers Time Force)
- Blue Mary Ryan (Fatal Fury/The King of Fighters)
- Ling Xiaoyu or Jun Kazama (Tekken)
- Gwen or Zoey (Total Drama)
- Mary or Gertie
- Elsa or Anna (Frozen (2013)) (Twilight Sparkle and Elsa are both magical)
- Ember Lumen (Elemental)
Counterparts (Boy Version)[]
- Thomas, Edward, Henry, James or Toby (Thomas and Friends) (Twilight Sparkle and Thomas are both the main protagonists)
- Ten Cents, Hercules, Warrior or OJ/Otis (TUGS/Salty's Lighthouse)
- Theodore, Truro, Inverness, or Digby (Theodore Tugboat)
- Wilson, Hodge, Chatsworth, or Old Puffer Pete (Chuggington)
- Sonic, Shadow, Knuckles, Tails, or Charmey (Sonic The Hedgehog)
- Stan Marsh (South Park)
- Fanboy or Kyle Bloodworth-Thomason (Fanboy and Chum Chum)
- Numbuh 1 (Codename: Kids Next Door)
- Noddy (Noddy's Toyland Adventures)
- Garfield or Orson (Garfield and Friends)
- Roddy (Flushed Away)
- Bugs Bunny (Looney Tunes)
- Professor Pat Pending (Wacky Races)
- Pooh, Rabbit, Owl or Christopher Robin (Winnie the Pooh)
- Sparkster (Rocket Knight Adventures)
- Sebastian the Crab (The Little Mermaid)
- Ryan (Zachary Swain)
- Mickey Mouse (Mickey Mouse)
- Hiro Hamada (Big Hero 6)
- Elliot or E.T. (E.T. the Extra-Terrestrial)
- Sora, Riku or Roxas (Kingdom Hearts, both Twilight Sparkle and Riku had a power within themselves)
- Godzilla, Gorosaurus or King Caesar (Godzilla, both Twilight Sparkle and Godzilla are both the main leaders)
- Ultraman (Ultraman)