Vodicka
From Scratchpad
[edit] Patient Information
Age: 24
Sex: Male
Diagnosed: 5/04/04
Location: Nebraska
Diagnosis: Large abdominal tumor & tumors in pelvic area. DSRCT
Hospital NIH in Bethesda MD
- Oncologist Dr. Langdon in NE, Dr. Fry at the NIH
No evidence of disease: 1/7/05
Relapse: 2/7/05
No evidence of disease: 3/23/05
Relapse, Stable disease: 5/05
No evidence of disease: 7/19/05
Relapse: 10/26/05
[edit] Treatment
Surgery
- Biopsy
- Central line
- Removed fluid
- Debulking - 80% of tumors removed, part of the diaphram, spleen, along with 12 lbs of tumor. Unable to resect tumor near vein that goes into liver, along with several tumors in the pelvic region.
- 2nd Surgery - Removed all visible tumors. Tumor came off the liver, all tumors in pelvic area removed, also removed appendix and gallbladder.
Chemotherapy
- P6 plus Dexrazoxane and Mesna
- Irinotecan
- EOCH - Etoposide, Vincristine, Doxirubicin, Cyclophosomide
- VP-16
Stem Cell
- Allogeneic transplant - received stem cells from sister
[edit] Time Line
| Date | Test | Treatment | Chemicals | Result |
|---|---|---|---|---|
| 5/8/04 | 0 | Surgery | 0 | Placed mediport, biopsy of tumor, removed liter and half of fluid from lung |
| 5/13/04 | 0 | Chemotherapy - Cycle 1 | P6 plus Dexrazoxane to protect heart, Mesna to protect bladder. | 0 |
| 5/21/04 | 0 | Minor Surgery | 0 | Mediport infection, removed line. |
| 5/28/04 | 0 | Minor surgery | 0 | Put in Broviac catheter |
| 6/3/04 | 0 | Chemotherapy Cycle 2 | P6 | 0 |
| 6/22/04 | 0 | Chemotherapy Cycle 3 | P6 | 0 |
| 7/12/04 | CT/PET | 0 | 0 | Tumors shrinking. |
| 7/19/04 | 0 | Chemotherapy Cyle 4 | P6 | 0 |
| 8/10/04 | 0 | Chemotherapy Cycle 5 | P6 | 0 |
| 9/1/04 | 0 | Debulking Surgery | 0 | 80% of tumors removed. Removed part of the diaphram and spleen along with 12 lbs. of tumor. Concerned about a tumor near vein that goes into the liver along with several small tumors in the pelvic region. |
| 9/23/04 | 0 | Chemotherapy Cyle 6 | P6 | 0 |
| 10/4/04 | 0 | Minor Surgery | 0 | Infection. Removed Broviac. |
| 10/26/04 | 0 | Minor Surgery. Chemotherapy Cycle 7 | P6 | Broviac put back in. |
| 11/9/04 | CT | Chemotherapy Cycle 8 | P6 | Good results |
| 12/8/04 | 0 | Surgery | 0 | Able to remove all visible tumors. The tumor came off the liver, tumors in the pelvic area were cleared out, apendix, and galblader removed. |
| 1/7/05 | CT | 0 | 0 | No evidence of disease. |
| 1/25/05 | CT | 0 | 0 | Look good |
| 2/7/05 | PET | 0 | 0 | Tumor has returned in four spots. |
| 2/14/05 | 0 | Chemotherapy - 5 days | Irinotecan | 0 |
| 3/7/05 | 0 | Chemotherapy - 5 days | Irinotecan | 0 |
| 3/21/05 | PET | 0 | 0 | Looked good, no light ups. |
| 3/23/05 | CT | 0 | 0 | No evidence of disease. |
| 4/12/05 | 0 | Begin Stem Cell Transplant | Chemotherapy -Etoposide, Doxorubicin, Vincristine | 0 |
| 5/28/05 | CT/PET | STem Cell process | Chemotherapy | Evidence of stable disease. |
| 6/14/05 | 0 | Engraphment started | 0 | Fevers and rash. |
| 7/15/05 | CT/PET | 0 | 0 | Stable disease. No growth. No reduction. |
| 7/19/05 | Liver Function Test | 0 | 0 | Elevated |
| 7/19/05 | PET | 0 | 0 | No evidence of disease. Cancer free. |
| 8/05 | 0 | 0 | 0 | 0 |
| 9/13/05 | CT/PET | 0 | 0 | No evidence of disease. |
| 9/22/05 | 0 | 0 | 0 | Infection in blood. |
| 10/26/05 | CT/PET | 0 | 0 | Scans showed some growth, a centimeter in one area and 1/2 a centimeter in another. |
| 10/28/05 | 0 | Chemotherapy | EPOC | 0 |
| 11/18/05 | CT | 0 | 0 | Stable disease. |
| 12/15/05 | CT | 0 | 0 | Stable disease. |
| 12/16/05 | 0 | Chemotherapy | 0 | 0 |
| 1/6/06 | CT | 0 | 0 | Stable disease. Has not grown. |
| 1/7/06 | 0 | Chemotherapy | 5 day EOCH - Etoposide, Doxorubicin, Vinristine, Cyclophosphamide, Prednisolone, G-CSF | 0 |
| 1/30/06 | CT/PET | 0 | 0 | Still some light up in tumors, but they have shrunk. |
| 2/28/06 | 0 | Chemotherapy | 5 day EOCH -Etoposide, Doxorubicin, Vinristine, Cyclophosphamide, Prednisolone, G-CSF | 0 |
| 3/30/06 | CT/PET | 0 | 0 | Not clean. |
| 4/06 | 0 | 0 | 0 | No chemo |
| 5/19/06 | CT/PET | GVHD from Transplant - not where doctors want it | 0 | After 7 weeks off chemo, the tumors that were there have grown and there are now 6 or 7 new spots. |
| 6/6/06 | CT/PET | Chemotherapy - started. | 0 | Tumors not responding to GVHD transplant (sibling stem cells) and are still growing. |
| 7/6/06 | 0 | Chemotherapy | 0 | 0 |
| 7/31/06 | PET/CT/MRI | 0 | 0 | PET shows improvement with tumors and lesions dying. CT and MRI show stable disease, with no growing or shrinking evident. |
| 8/2/06 | 0 | Chemotherapy | 0 | 0 |
| 8/28/06 | 0 | Chemotherapy | EOCH | 0 |
| 9/06 | 0 | 0 | 0 | 0 |
| 10/4/06 | CT | 0 | 0 | Stable disease. |
| 11/6/06 | PET | Chemo- VP-16 | 0 | Tumor growth. Kidney and pelvic region tumors have increased |
| 11/7/06 | CT | Chemo- VP-16 | 0 | New growth behind liver that was pressing on a vein. Pocket of air below heart |
| 12/06 | 0 | Chemo- VP-16 | 0 | 0 |
| 1/4/07 | CT | 0 | 0 | New growth. Changed chemo as it is not working. |
| 2/07 | 0 | Chemotherapy | New chemo mixed with Irinotecan | 0 |
| 3/07 | 0 | 0 | 0 | 0 |
| 4/07 | 0 | 0 | 0 | 0 |
| 5/17/07 | CT | Chemotherapy | Change in chemotherapy Irinotecan with a form of Vincristine. Next scans are July 9. | Stable disease. |
| 6/07 | 0 | 0 | 0 | 0 |
| 7/07 | 0 | 0 | 0 | 0 |
| 8/07 | 0 | 0 | 0 | 0 |
| 9/07 | 0 | 0 | 0 | 0 |
| 10/07 | 0 | 0 | 0 | 0 |
| 11/07 | 0 | 0 | 0 | 0 |
| 12/07 | 0 | 0 | 0 | 0 |
| 1/08 | 0 | 0 | 0 | 0 |
| 2/08 | 0 | 0 | 0 | 0 |
| 3/08 | 0 | 0 | 0 | 0 |
| 4/08 | 0 | 0 | 0 | 0 |
| 0 | 0 | 0 | 0 | 0 |
| 0 | 0 | 0 | 0 | 0 |
| 0 | 0 | 0 | 0 | 0 |
| 0 | 0 | 0 | 0 | 0 |
| 0 | 0 | 0 | 0 | 0 |
| 0 | 0 | 0 | 0 | 0 |
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