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In Memory

Smsunfl Ryan

Patient Information

Age: 24

Sex: Male

Diagnosed: 5/04/04

Location: Nebraska

Diagnosis: Large abdominal tumor & tumors in pelvic area. DSRCT

Hospital NIH in Bethesda MD

Oncologist Dr. Langdon in NE, Dr. Fry at the NIH

No evidence of disease: 1/7/05

Relapse: 2/7/05

No evidence of disease: 3/23/05

Relapse, Stable disease: 5/05

No evidence of disease: 7/19/05

Relapse: 10/26/05

Passed away: 3/11/09

Caringbridge Journal

Treatment

Surgery

Biopsy
Central line
Removed fluid
Debulking - 80% of tumors removed, part of the diaphram, spleen, along with 12 lbs of tumor. Unable to resect tumor near vein that goes into liver, along with several tumors in the pelvic region.
2nd Surgery - Removed all visible tumors. Tumor came off the liver, all tumors in pelvic area removed, also removed appendix and gallbladder.

Chemotherapy

P6 plus Dexrazoxane and Mesna
Irinotecan
EOCH - Etoposide, Vincristine, Doxirubicin, Cyclophosomide
VP-16

Stem Cell

Allogeneic transplant - received stem cells from sister

Time Line

Date Test Treatment Chemicals Result
5/8/04 0 Surgery 0 Placed mediport, biopsy of tumor, removed liter and half of fluid from lung
5/13/04 0 Chemotherapy - Cycle 1 P6 plus Dexrazoxane to protect heart, Mesna to protect bladder. 0
5/21/04 0 Minor Surgery 0 Mediport infection, removed line.
5/28/04 0 Minor surgery 0 Put in Broviac catheter
6/3/04 0 Chemotherapy Cycle 2 P6 0
6/22/04 0 Chemotherapy Cycle 3 P6 0
7/12/04 CT/PET 0 0 Tumors shrinking.
7/19/04 0 Chemotherapy Cyle 4 P6 0
8/10/04 0 Chemotherapy Cycle 5 P6 0
9/1/04 0 Debulking Surgery 0 80% of tumors removed. Removed part of the diaphram and spleen along with 12 lbs. of tumor. Concerned about a tumor near vein that goes into the liver along with several small tumors in the pelvic region.
9/23/04 0 Chemotherapy Cyle 6 P6 0
10/4/04 0 Minor Surgery 0 Infection. Removed Broviac.
10/26/04 0 Minor Surgery. Chemotherapy Cycle 7 P6 Broviac put back in.
11/9/04 CT Chemotherapy Cycle 8 P6 Good results
12/8/04 0 Surgery 0 Able to remove all visible tumors. The tumor came off the liver, tumors in the pelvic area were cleared out, apendix, and galblader removed.
1/7/05 CT 0 0 No evidence of disease.
1/25/05 CT 0 0 Look good
2/7/05 PET 0 0 Tumor has returned in four spots.
2/14/05 0 Chemotherapy - 5 days Irinotecan 0
3/7/05 0 Chemotherapy - 5 days Irinotecan 0
3/21/05 PET 0 0 Looked good, no light ups.
3/23/05 CT 0 0 No evidence of disease.
4/12/05 0 Begin Stem Cell Transplant Chemotherapy -Etoposide, Doxorubicin, Vincristine 0
5/28/05 CT/PET STem Cell process Chemotherapy Evidence of stable disease.
6/14/05 0 Engraphment started 0 Fevers and rash.
7/15/05 CT/PET 0 0 Stable disease. No growth. No reduction.
7/19/05 Liver Function Test 0 0 Elevated
7/19/05 PET 0 0 No evidence of disease. Cancer free.
8/05 0 0 0 0
9/13/05 CT/PET 0 0 No evidence of disease.
9/22/05 0 0 0 Infection in blood.
10/26/05 CT/PET 0 0 Scans showed some growth, a centimeter in one area and 1/2 a centimeter in another.
10/28/05 0 Chemotherapy EPOC 0
11/18/05 CT 0 0 Stable disease.
12/15/05 CT 0 0 Stable disease.
12/16/05 0 Chemotherapy 0 0
1/6/06 CT 0 0 Stable disease. Has not grown.
1/7/06 0 Chemotherapy 5 day EOCH - Etoposide, Doxorubicin, Vinristine, Cyclophosphamide, Prednisolone, G-CSF 0
1/30/06 CT/PET 0 0 Still some light up in tumors, but they have shrunk.
2/28/06 0 Chemotherapy 5 day EOCH -Etoposide, Doxorubicin, Vinristine, Cyclophosphamide, Prednisolone, G-CSF 0
3/30/06 CT/PET 0 0 Not clean.
4/06 0 0 0 No chemo
5/19/06 CT/PET GVHD from Transplant - not where doctors want it 0 After 7 weeks off chemo, the tumors that were there have grown and there are now 6 or 7 new spots.
6/6/06 CT/PET Chemotherapy - started. 0 Tumors not responding to GVHD transplant (sibling stem cells) and are still growing.
7/6/06 0 Chemotherapy 0 0
7/31/06 PET/CT/MRI 0 0 PET shows improvement with tumors and lesions dying. CT and MRI show stable disease, with no growing or shrinking evident.
8/2/06 0 Chemotherapy 0 0
8/28/06 0 Chemotherapy EOCH 0
9/06 0 0 0 0
10/4/06 CT 0 0 Stable disease.
11/6/06 PET Chemo- VP-16 0 Tumor growth. Kidney and pelvic region tumors have increased
11/7/06 CT Chemo- VP-16 0 New growth behind liver that was pressing on a vein. Pocket of air below heart
12/06 0 Chemo- VP-16 0 0
1/4/07 CT 0 0 New growth. Changed chemo as it is not working.
2/07 0 Chemotherapy New chemo mixed with Irinotecan 0
3/07 0 0 0 0
4/07 0 0 0 0
5/17/07 CT Chemotherapy Change in chemotherapy Irinotecan with a form of Vincristine. Next scans are July 9. Stable disease.
6/07 0 0 0 0
7/07 0 0 0 0
8/07 0 0 0 0
9/07 0 0 0 0
10/07 0 0 0 0
11/07 0 0 0 0
12/07 0 0 0 0
1/08 0 0 0 0
2/08 0 0 0 0
3/08 0 0 0 0
4/08 0 0 0 0
5/08 0 0 0 0
6/08 0 0 0 0
7/08 0 0 0 0
8/08 0 0 0 0
9/08 0 0 0 0
10/08 0 0 0 0
11/08 0 0 0 0
12/08 0 0 0 0
1/09 0 0 0 0
2/09 0 0 0 0
3/11/09 0 0 0 Passed away

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