- Tommy Pickles as Rex
- Phil DeVille as Woog
- Lil DeVille as Dweeb
- Kimi Finster as Elsa
- Grandpa Lou as Captian Neweyes
- Dil Pickles as Vorb
- Bart (from The Simpsons) as Louie
- Lisa (from The Simpsons) as Cecilia
- Timmy McNulty as Professor Screweyes
- Charlotte Pickles as Dr. Bleeb
- Petrie (from The Land Before Time) as Buster the Bird
- Petrie's Mother (from The Land Before Time) as Buster's Mother
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