- Robin Sena as Marge Simpson
- Amon as Homer Simpson
- Haruto Sakaki as Mayor Joe Quimby
- Michael Lee as Bart Simpson
- Miho Karasuma as Allison Taylor
- Yurika Dojima as Maggie Simpson
- Takuma Zaizen as Mr. Burns
- Shintaro Kosaka as Moe Syzlak
- Master as Grandpa Abe Simpson
- Shohei Hattori as Ned Flanders
- Toko Masaki as Waylon Smithers, Jr.
- Shunji Nagira as Dr. Julius Hibbert
- and more
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